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REFERÊNCIAS

[1] - CDC. “Phthalates – Fact Sheet” (2009) – Homepage: http://www.cdc.gov/biomonitoring/pdf/Pthalates_FactSheet.pdf

[2] - Ceresana "Market Study: Plasticizers (3rd edition)" - Homepage: http://www.ceresana.com/en/market-studies/additives/plasticizers/ - Acedido a 16/05/2016

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[4] - Frederiksen, H., Skakkebaek, N. E., & Andersson, A. M. (2007). Metabolism of phthalates in humans.Molecular nutrition & food research, 51(7), 899-911.

[5] - http://www.plasticisers.org/en_GB/plasticisers - 20/05/2016

[6] - Stales, C. A., Peterson, D. R., Parkerton, T. F., & Adams, W. J. (1997). The environmental fate of phthalate esters: a literature review. Chemosphere,35(4), 667-749.

[7] - Cousins, I., & Mackay, D. (2000). Correlating the physical–chemical properties of phthalate esters using thethree solubility'approach. Chemosphere, 41(9), 1389-1399.

[8] - Heng, K. (2011). Mechanism of action of phthalate endocrine disruptors in male reproductive development.

[9] - López-Carrillo, L., Hernández-Ramírez, R. U., Calafat, A. M., Torres-Sánchez, L., Galván-Portillo, M., Needham, L. L., ... & Cebrián, M. E. (2010). Exposure to phthalates and breast cancer risk in northern Mexico. Environmental health perspectives, 118(4), 539.

[10] - Loureiro, I. R. (2002). A importância e ocorrência de ftalatos em água potável e no ecossistema da Baía de Guanabara (Doctoral dissertation, PUC-Rio).

[11] - Lovekamp-Swan, T., & Davis, B. J. (2003). Mechanisms of phthalate ester toxicity in the female reproductive system. Environmental health perspectives, 111(2), 139.

[12] - Patrick, L. (2009). Thyroid disruption: mechanisms and clinical implications in human health. Alternative Medicine Review, 14(4), 326-347.

[13] - http://www.ecycle.com.br/component/content/article/63/2246-o-que-sao-disruptores-endocrinos-como-agem-hormonio-alteracao-naturais-sinteticos-ocorrencia-dietilestibestrol-pesticida-ddt-higiene-pessoa-cosmeticos-aditivos-alimentares-contaminantes-ftalatos-bisfenol-a-parabenos-chumbo-triclosan-cancer-asma-parkinson.html - Acedido a 03/05/2016

[14] - Svechnikov, K., Izzo, G., Landreh, L., Weisser, J., & Söder, O. (2010). Endocrine disruptors and Leydig cell function. BioMed Research International, 2010.

[15] - https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~xRR90K:1 - Acedido em 25/04/2016

[16] - Mikula, P. Ř. E. M. Y. S. L., Svobodova, Z. D. E. Ň. K. A., & Smutna, M. I. R. I. A. M. (2005). Phthalates: Toxicology and food safety-a review. Czech journal of food sciences, 23(6), 217.

[17] - Rusyn, I., Peters, J. M., & Cunningham, M. L. (2006). Modes of action and species-specific effects of di-(2-ethylhexyl) phthalate in the liver. Critical reviews in toxicology, 36(5), 459-479.

[18] - CSTEE; Human and Wildlife Health Effects of Endocrine Disrupting Chemicals, with Emphasis on Wildlife and on Ecotoxicology Test Methods, Committee on Toxicity, Ecotoxicity and the Environment, (CSTEE), 1999

[19] - Bila, D. M., & Dezotti, M. (2007). Endocrine disrupters in the enviroment: part 1-effects and consequences. Química Nova, 30(3), 651-666.

[20] - K. Svechnikov, I. Svechnikova, and O. Soder, “Inhibitory ¨ effects of mono-ethylhexyl phthalate on steroidogenesis in immature and adult rat Leydig cells in vitro,” Reproductive Toxicology, vol. 25, no. 4, pp. 485–490, 2008.

[21] - Yao, P. L., Lin, Y. C., & Richburg, J. H. (2012). Mono-(2-ethylhexyl) phthalate (MEHP) promotes invasion and migration of human testicular embryonal carcinoma cells. Biology of reproduction,86(5), 160.

[22] - Kluwe, W. M., Haseman, J. K., & Huff, J. E. (1983). The carcinogenicity of d1 (2‐ethylhexyl) phthalate (dehp) in perspective.

[23] - Kluwe, W. M. (1986). Carcinogenic potential of phthalic acid esters and related compounds: structure-activity relationships. Environmental health perspectives, 65, 271.

[24] - Rusyn, I., Peters, J. M., & Cunningham, M. L. (2006). Modes of action and species-specific effects of di-(2-ethylhexyl) phthalate in the liver. Critical reviews in toxicology, 36(5), 459-479.

[25] - Ganning, A. E., Brunk, U., & Dallner, G. (1984). Phthalate esters and their effect on the liver.Hepatology, 4(3), 541-547.

(26] - Heudorf, U., Mersch-Sundermann, V., & Angerer, J. (2007). Phthalates: toxicology and exposure.International journal of hygiene and environmental health, 210(5), 623-634.

[27] - Fontelles, J. B., & Clarke, C. (2005). Directive 2005/84/EC of the European Parliament and of the Council of 14 December 2005 amending for the 22nd time Council Directive 76/69/EEC on the approximation of the laws, regulations and administrative provisions of the Men Der States relating to restrictions on the marketing and use of certain dangerous substances and preparations (phthalates in toys and childcare articles). Official Journal of the European Union, 48, 40-3.

[28] - Plasticisers & Flexible PVC information centre, disponível em: http://www.plasticisers.org/en_GB/regulation/reach, acedido a: 13 de Maio de 2016

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